Published 2010-06-10
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Artículo producto de Investigación

Control predictivo aplicado a la dosificación automática de insulina en pacientes con diabetes tipo 1

DOI: https://doi.org/10.22490/25391887.682
Diego Fernando Sendoya Losada
Faiber Ignacio Robayo Betancourt
John F. Fredy Perafán Javela
Victoria Eugenia Gutiérrez Cuevas
Miosotis Borrero Ortiz

Control engineering influences the modern medicine through robotic surgery, electrophysiological systems (pacemakers and automatic implantable defibrillators), life support systems (ventilators and artificial hearts), and image-guided surgery. An additional area of medicine suited for applications of control is clinical pharmacology, in which.

mathematical modeling plays a prominent role. Although numerous drugs are available for treating disease, proper dosing is often imprecise, resulting in increased costs, morbidity and mortality.

In this work, a potential application of the control engineering to clinical pharmacology, specifically the control of drug dosing is presented. The principal goal is to develop a device in order to control the blood glucose concentration for people with type 1 diabetes, using a predictive control algorithm.

An analysis upon several dynamic relationships between the glucose and the insulin available in the literature must be performed, in order to find and select a proper model for prediction. This model will permit to design an adequate controller.

Finally, the controller robustness will be tested taking into account assumptions as: the algorithm must be applied on different patients and the patient-model could change along the time.

 

keywords: drug dosing automatic control, diabetes, insulin control, based model control
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How to Cite

Sendoya Losada, D. F., Robayo Betancourt, F. I., Perafán Javela, J. F. F., Gutiérrez Cuevas, V. E., & Borrero Ortiz, M. (2010). Control predictivo aplicado a la dosificación automática de insulina en pacientes con diabetes tipo 1. Revista De Investigaciones UNAD, 9(2), 203-211. https://doi.org/10.22490/25391887.682
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