Potencial antimicrobiano de extractos de plantas medicinales y sus mezclas frente a bacterias asociadas con conjuntivitis

Wendy Johanna  Velasco Garcia; Ludy C.  Pabón Baquero; Patricia  Hernández-Rodríguez

doi:10.22490/24629448.5294

Vol. 19 No. 36 (2021)

Published 2021-09-20

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Research Article (before OJS)

Antimicrobial potential of plant extracts and their mixtures against bacteria associated with conjunctivitis

DOI: https://doi.org/10.22490/24629448.5294

Wendy Johanna Velasco Garcia Universidad de La Salle

Ludy C. Pabón Baquero Universidad de La Salle

Patricia Hernández-Rodríguez Universidad de La Salle

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Abstract
References

Introduction. Bacterial conjunctivitis is one of the ocular infections with the highest rate of ophthalmic consultation, being the Staphylococcus genus the etiological agent that presents the greatest resistance to antibiotics. Objective. To determine the antimicrobial potential of medicinal plant extracts and their mixtures against bacteria associated with conjunctivitis. Methods. From plants such as Belladonna, Calendula, Basil, Achiote and Romerillo, ethanolic extracts were prepared and their antibacterial potential against S. aureus and S. epidermidis was evaluated by means of disk diffusion and tube dilution techniques. The effect of the mixtures was determined for the extract with the best activity and the antibiotic with the highest inhibition halo through the board technique. Results. It was found that the extract with the highest potential for S. aureus was that of annatto (leaves) with an inhibition halo of 13 mm and MICs of 15 mg / mL, while for S. epidermidis it was those of annatto leaves and fruits with halos of 16.6 and 9.6 mm and MICs of 15 and 30 mg / mL respectively. In relation to the combinations, the annatto extract and ciprofloxacin showed a partial synergistic effect for S. aureus with a CFI of 0.83 and an additive effect for S. epidermidis with a CFI of 1.84. Conclusions. This work constitutes the basis for future
research aimed at the development of bioproducts for ocular use that can be considered as an alternative in the treatment of infections caused by Staphylococcus.

keywords: conjunctivitis, antibacterial activity, plant extracts, staphylococcus, infection

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Velasco Garcia, W. J. ., Pabón Baquero, L. C. ., & Hernández-Rodríguez, P. . (2021). Antimicrobial potential of plant extracts and their mixtures against bacteria associated with conjunctivitis. NOVA Biomedical Sciences Journal, 19(36), 95-108. https://doi.org/10.22490/24629448.5294

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Antimicrobial potential of plant extracts and their mixtures against bacteria associated with conjunctivitis

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