El papel del biofilm en el proceso infeccioso y la resistencia

María Teresa Herrera Mendoza; Bac Esp.

doi:10.22490/24629448.10

Vol. 2 No. 2 (2004)

Published

2004-12-15

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Infectious Process and Resistance Biofilm Role.

DOI: https://doi.org/10.22490/24629448.10

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Article of Review (before OJS)

María Teresa Herrera Mendoza; Bac Esp. Universidad Colegio Mayor de Cundinamarca.

Biofilm is a cell population which grows up together in a wrapped surface in a exopolysaccharide matrix which protects them of antibiotic attacks. More than 60% of all microbial infection is caused by Biofilm, to raise the resistance of these antimicrobial communities there are several mechanisms among others; antibiotic inactivity by extracellular polymerous or enzymatic alteration, grow rate diminished due to nutrient limitation, phenotypic changes in bacterial cells as a result of acquisition of resistance gene into biofilm and the persistence of a small cell group in bacterial community.

The prognostic to treat and quit out biofilms is not encouraging in the immediate future. Is necessary and urgent to develop new medicines to counteract infectious on which biofilm is involved. Biofilm infection is evident with symptoms that clinically revert to antibiotic treatment. American Health Institute issued: “more than 60% of all microbian infectious are caused by biofilms”, also a 60% is attributed to them in nosocomial infections, increasing in this way hospitable stay, attention fees and mortality; due to its large resistance to antimicrobial a thousand times more than cells which live in planktonic way. The objective of the current revision is to illustrate about biofilm formation and its role in the infectious process.

biofilm, infection, resistance, persistence, antibiotics, infectious process.

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Herrera Mendoza; Bac Esp., M. T. (2004). Infectious Process and Resistance Biofilm Role. NOVA Biomedical Sciences Journal, 2(2), 71-80. https://doi.org/10.22490/24629448.10

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