Productos farmacéuticos y de cuidado personal presentes en aguas superficiales, de consumo humano y residuales en el departamento de Córdoba, Colombia

Joel Alean Flórez; Daniela Márquez Méndez; Saudith María Burgos Núñez; Germán Enamorado-Montes; José Marrugo Negrete

doi:10.22490/21456453.4231

Vol. 12 No. 2 (2021)

Published 2021-06-02

license

Área Ambiental

Pharmaceutical and personal care products present in surface, drinking and wastewater in the department of Cordoba, Colombia

DOI: https://doi.org/10.22490/21456453.4231

Alean-Flórez, J. Universidad de Córdoba

Márquez-Méndez, D. Universidad de Córdoba

Burgos-Núñez, S. Universidad de Córdoba

Enamorado-Montes, G. Universidad de Córdoba

Marrugo-Negrete, J. Universidad de Córdoba

PDF (Spanish)

Visor (Spanish)

HTML (Spanish)

XML (Spanish)

Epub (Spanish)

Movil (Spanish)

Abstract
References

Contextualization: Advancement in the Sensitivity of Analytical Techniques developed in recent decades contribute to identify and quantify the presence of various pollutants in the aquatic environment, within this group of pollutants we have the emerging pollutants (EP) which are mainly organic compounds present as personal care and hygiene products, antibiotics, hormones, plasticizers, drugs and other products that are dumped into water sources altering the balance of these ecosystems.

Knowledge gap: Several studies show that emerging pollutants may negatively affect aquatic life and human health. To date, in the city of Monteria and in the department of Córdoba, any investigations has been reported that allows evidence of the presence of emerging pollutants in surface water, for human and residual consumption.

Purpose: This study aimed to evaluate the presence of five common emerging pollutants: naproxen, ibuprofen, gemfibrozil, caffeine and triclosan in samples of water for human, residual and surface consumption collected in the north of Colombia, representing thus one of the first studies to report the presence of these compounds in water sources in this region.

Methodology: Solid phase extraction (SPE) was used for the analysis of the water samples; the detection and quantification were carried out by high efficiency liquid chromatography with a diode array detector and molecular fluorescence (HPLC-DAD-FLD).

Results and conclusions: Ibuprofen was the most frequently found compound in the water samples, opposite to triclosan, which was the least detected (2.25 µg / L), caffeine was found with a maximum of 43.38 µg/L, while concentrations of naproxen and ibuprofen were between 0.047 and 10.21 µg/L, which is an important health concern due to presence of these compounds in drinking waters. These results show the anthropogenic pressure exerted on the aquatic compartments, which could become an environmental problem that may affect the dynamics and ecosystem services. It was found that the water supply plants do not take into account the presence of these compounds in their purification systems, which could become a public health issue in the future.

Ibuprofen was found most frequently in all three the water sources, in contrast to triclosan, which was the least frequently detected at low levels (2.25 µg / L), caffeine was found with a maximum of 43.38 µg/L, while naproxen and ibuprofen concentrations were between 0.047 and 10.21 µg/L. These results show the anthropogenic pressure exerted on the aquatic compartments, which could become an environmental problem in the future. At the same time, it shows that the water supply plants do not take into account the presence of these compounds in their purification systems; Although the concentrations reported are low, it does not indicate that they do not represent any type of risk

keywords: Drinking water, surface water, pollutants, pharmaceutical compounds

Acosta-Ordoñez, K. D., & Acosta-Ordoñez, K. (2013). La economía de las aguas del río sinú. Documentos De Trabajo Sobre Economía Regional Y Urbana; no.194,

Bound, J. P., & Voulvoulis, N. (2005). Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United kingdom. Environmental Health Perspectives, 113(12), 1705–11. https://doi.org/10.1289/EHP.8315.

APHA, 2005. Standard Methods for the Examination of Water and Wastewater 21th Ed. American Water Works Association. Water Environment Federation, Washington, DC.

Aristizabal-Ciro, C., Botero-Coy, A. M., López, F. J., & Peñuela, G. A. (2017). Monitoring pharmaceuticals and personal care products in reservoir water used for drinking water supply. Environmental Science and Pollution Research, 24(8), 7335-7347.

Arrubla, J. P., Cubillos, J. A., Ramírez, C. A., Arredondo, J. A., Arias, C. A., & Paredes, D. (2016). Pharmaceutical and personal care products in domestic wastewater and their removal in anaerobic treatment systems: Septic tank-up flow anaerobic filter. Ingeniería E Investigación, 36(1), 70-78

Botero-Coy, A. M., Martínez-Pachón, D., Boix, C., Rincón, R. J., Castillo, N., Arias-Marín, L. P., . . . Hernández, F. (2018). An investigation into the occurrence and removal of pharmaceuticals in colombian wastewater. Science of the Total Environment, 642, 842-853.

Buerge, I. J., Poiger, T., Müller, M. D., & Buser, H. R. (2003). Caffeine, an anthropogenic marker for wastewater contamination of surface waters. Environmental Science and Technology, 37(4), 691–700. https://doi.org/10.1021/es020125z

Carballa, M., Omil, F., Lema, J. M., Llompart, M., Garcı́a-Jares, C., Rodrı́guez, I., … Ternes, T. (2004). Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant. Water Research, 38(12), 2918–2926. https://doi.org/10.1016/J.WATRES.2004.03.029

Da Silva, B. F., Jelic, A., López-Serna, R., Mozeto, A. A., Petrovic, M., & Barceló, D. (2011). Occurrence and distribution of pharmaceuticals in surface water, suspended solids and sediments of the ebro river basin, spain. Chemosphere, 85(8), 1331-1339.

De Voogt, P., Janex-Habibi, M. L., Sacher, F., Puijker, L., & Mons, M. (2009). Development of a common priority list of pharmaceuticals relevant for the water cycle. Water Science and Technology, 59(1), 39-46.

Escobar, J. (2003). La contaminación de los ríos y sus efectos en las áreas costeras y el mar (Vol. 50). United Nations Publications.

Fang, Y., Karnjanapiboonwong, A., Chase, D. A., Wang, J., Morse, A. N., & Anderson, T. A. (2012). Occurrence, fate, and persistence of gemfibrozil in water and soil. Environmental Toxicology and Chemistry, 31(3), 550–555. https://doi.org/10.1002/etc.1725

Fent, K., Weston, A. A., & Caminada, D. (2006). Ecotoxicology of human pharmaceuticals. Aquatic Toxicology, 76(2), 122–159. https://doi.org/10.1016/j.aquatox.2005.09.009

Ferreira, A. P. (2005). Caffeine as an environmental indicator for assessing urban aquatic ecosystems. Cadernos De Saúde Pública, 21, 1884-1892.

Food and Drug Administration. (2017). Safety and Effectiveness of Consumer Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use. Retrieved from http://www.regulations.gov

Heberer, T. (2002). Tracking persistent pharmaceutical residues from municipal sewage to drinking water. Journal of Hydrology, 266(3–4), 175–189. https://doi.org/10.1016/S0022-1694(02)00165-8

Hernando, M. D., Mezcua, M., Fernández-Alba, A. R., & Barceló, D. (2006). Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta, 69(2), 334-342.

Jiang, J.-Q., Zhou, Z., & Sharma, V. K. (2013). Occurrence, transportation, monitoring and treatment of emerging micro-pollutants in waste water — A review from global views. Microchemical Journal, 110, 292–300. https://doi.org/10.1016/j.microc.2013.04.014

Jones, O. A. H., Voulvoulis, N., & Lester, J. N. (2001). Human Pharmaceuticals in the Aquatic Environment a Review. Environmental Technology, 22(12), 1383–1394. https://doi.org/10.1080/09593330.2001.11090873

Murray, K. E., Thomas, S. M., & Bodour, A. A. (2010). Prioritizing research for trace pollutants and emerging contaminants in the freshwater environment. Environmental Pollution, 158(12), 3462–3471. https://doi.org/10.1016/J.ENVPOL.2010.08.009

Madera-Parra, C. A., Jiménez-Bambague, E. M., Toro-Vélez, A. F., Lara-Borrero, J. A., Bedoya-Ríos, D. F., & Duque-Pardo, V. (2018). Estudio exploratorio de la presencia de microcontaminantes en el ciclo urbano del agua en colombia: Caso de estudio santiago de cali. Revista Internacional De Contaminación Ambiental, 34(3), 475-487.

Navarro, A. (2019). Presencia e impacto de los contaminantes emergentes en aguas superficiales. En Tópicos sobre contaminantes y contaminación del agua. (1.ra ed., p 36). Ciudad de Mexico: Clave editorial. Recuperado de ISBN: 978-607-98708-0-5 (UTIM).

Parson, J. J. (1952). The settlement of the sinu valley of colombia. Geographical Review, 42(1), 67-86.

Pemberthy, D., Padilla, Y., Echeverri, A., & Peñuela, G. A. (2020). Monitoring pharmaceuticals and personal care products in water and fish from the gulf of urabá, colombia. Heliyon, 6(6), e04215.

Peña-Álvarez, A., & Castillo-Alanís, A. (2015). Identificación y cuantificación de contaminantes emergentes en aguas residuales por microextracción en fase sólida-cromatografía de gases-espectrometría de masas (MEFS-CG-EM). TIP Revista Especializada En Ciencias Químico-Biológicas, 18(1), 29-42.

Comber, S., Gardner, M., Sörme, P., Leverett, D., & Ellor, B. (2018). Active pharmaceutical ingredients entering the aquatic environment from wastewater treatment works: a cause for concern?. Science of the total environment, 613, 538-547.

Rainsford, K. D. (2011). No title. Fifty Years since the Discovery of Ibuprofen.

Roa, M. V. S., & Cárdenas, G. G. (2013). Condición de venta de analgésicos antiinflamatorios no esteroides, legalmente autorizados para su comercialización en colombia. estrategias de uso racional. Revista Colombiana De Ciencias Químico-Farmacéuticas, 42(2), 145-168.

Santos, J. L., Aparicio, I., Alonso, E., & Callejón, M. (2005). Simultaneous determination of pharmaceutically active compounds in wastewater samples by solid phase extraction and high-performance liquid chromatography with diode array and fluorescence detectors. Analytica Chimica Acta, 550(1-2), 116-122.

Santos, L. H. M. L. M., Gros, M., Rodriguez-Mozaz, S., Delerue-Matos, C., Pena, A., Barceló, D., & Montenegro, M. C. B. S. M. (2013). Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: Identification of ecologically relevant pharmaceuticals. Science of The Total Environment, 461–462, 302–316. https://doi.org/10.1016/j.scitotenv.2013.04.077

Saussereau, E., Lacroix, C., Guerbet, M., Cellier, D., Spiroux, J., & Goullé, J.-P. (2013). Determination of Levels of Current Drugs in Hospital and Urban Wastewater. Bulletin of Environmental Contamination and Toxicology, 91(2), 171–176. https://doi.org/10.1007/s00128-013-1030-7

Uslu, M. O., Jasim, S., Arvai, A., Bewtra, J., & Biswas, N. (2013). A Survey of Occurrence and Risk Assessment of Pharmaceutical Substances in the Great Lakes Basin. Ozone: Science & Engineering, 35(4), 249–262. https://doi.org/10.1080/01919512.2013.793595

US EPA. (2009). Ibuprofen. Retrieved July 8, 2018, from https://iaspub.epa.gov/tdb/pages/contaminant/contaminantOverview.do

US EPA. (2018). Triclosan. Retrieved July 8, 2018, from https://www.epa.gov/ingredients-used-pesticide-products/triclosan

Zhang, Y., Geißen, S.-U., & Gal, C. (2008). Carbamazepine and diclofenac: Removal in wastewater treatment plants and occurrence in water bodies. Chemosphere, 73(8), 1151–1161. https://doi.org/10.1016/J.CHEMOSPHERE.2008.07.086

license

How to Cite

Alean Flórez, J., Márquez Méndez, D., Burgos Núñez, S. M., Enamorado-Montes, G., & Marrugo Negrete, J. (2021). Pharmaceutical and personal care products present in surface, drinking and wastewater in the department of Cordoba, Colombia. Revista De Investigación Agraria Y Ambiental, 12(2), 179-197. https://doi.org/10.22490/21456453.4231

Download Citation

Almétricas

Metrics

Archivos descargados

2,594

| |

Pharmaceutical and personal care products present in surface, drinking and wastewater in the department of Cordoba, Colombia

Most read articles by the same author(s)