Published
2021-06-02
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Immune response in calves born to cows vaccinated or not vaccinated with bacterin against neumoenteritis

DOI: https://doi.org/10.22490/21456453.3620
Section
Área Pecuaria
Castrillón, M. Universidad Nacional de Colombia Sede Palmira
Campos, R. Universidad Nacional de Colombia Sede Palmira

Contextualization: Neonatal diarrhea is a common pathology in calves, causing high mortality and decreased livestock productivity.

 

Knowledge gap: A proposed option for their control is the immunization of dams against enteropathogens, which has not been sufficiently researched in Colombia.

 

Purpose: The objective of this work was to determine indicators of passive immunity in bovine neonates, born of cows vaccinated with commercial bacterin against pneumoenteritis applied in the last third of gestation.

 

Methodology: Twenty-one crossbred pregnant cows were distributed in three groups: T1, control; T2, application of a dose of the biological 30 days prepartum, and T3 application of two doses at 30 and 15 days prepartum; a fourth T4 group for active immunity determination, of neonates vaccinated with bacterin at 24 hours of life. The experimental period for cows ranging from 30 days antepartum until calving, calves between 24 and 72 hours after birth.

 

Results and conclusions: In the calves, indicators of protein metabolism and immunoglobulins (Ig) were analyzed. Colostrum quality, five indicators of protein metabolism and cortisol as an immune modulator were analyzed in cows, they did not present significant statistical differences between treatments, with the exception of T3 in AST. In neonates IgA and IgG had no significant differences between treatments or for time. IgM and albumin had significant differences for treatments or time, while globulins and total proteins only for time. No effect of bacterin applications was evidenced and no failure was found in the transfer of passive immunity.