Evaluación la acción antibacteriana de tres extractos etanólicos de propóleos de los municipios de Sevilla, Cartago y Armenia, Colombia contra MRSA (Staphylococcus aureus resistente a meticilina)

Luz Elena  Triana; Armando  Lucumi

doi:10.22490/24629448.8195

Vol. 22 No. 42 (2024): Primer número 2024

Published 2024-06-22

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Antibacterial activity of three ethanolic extracts of propolis from the municipalities of Sevilla, Cartago, and Armenia, Colombia, against MRSA (Methicillin-Resistant Staphylococcus aureus)

DOI: https://doi.org/10.22490/24629448.8195

Luz Elena Triana Universidad Libre de Colombia

Armando Lucumi Universidad Libre de Colombia

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Abstract
References

Introduction: Staphylococcus aureus is a pathogen commonly associated with hospital and community-acquired infections, particularly methicillin-resistant strains that impose limi- tations on treatment options. The resistance of these strains to beta-lactam antibiotics has spurred the search for new antimicrobial sources, and natural products such as propolis extracts have demonstrated efficacy against Methicillin-Resistant Staphylococcus aureus. The an- timicrobial activity of propolis depends to the flora used by the bees to make the propolis. Aim: This study aims to determine the antibacterial activity of three ethanolic extracts of propolis from the municipalities of Sevilla, Cartago, and Armenia, Colombia, against Methicillin-Resistant Staphylococcus aureus. Methodology: The methodology involved obtaining ethanolic extracts of propolis collected from different regions of Colombia, followed by fractionation and identification of the propolis with the highest bactericidal activity. Subsequently, an analysis using gas chromatography coupled with mass spectro- metry (GC-MS) was identified the predominant compound in the selected fractions. Re- sults: All three propolis samples evaluated in this study demonstrated bactericidal activity at concentration of 10 mg/mL, with the Cartago propolis showing concentrations below 5 mg/mL. Chromatographic analysis identified 3-Hexadecyloxycarbonyl-5-(2-hydroxye- thyl) as the predominant compound. Conclusion: In conclusion, the need for additional research to understand the pharmacological potential of Colombian propolis, specifically the bactericidal activity of Cartago propolis against Methicillin-Resistant Staphylococcus aureus.

keywords: MRSA, Antimicrobial activity, Colombian propolis

Foster TJ. Can β-Lactam Antibiotics Be Resurrected to Combat MRSA? Trends Microbiol. 2019;27(1):26–38.

Sforcin JM. Biological properties and therapeutic applications of propolis. Phyther Res. 2016;30(6):894–905.

Ripari N, Beatriz Toti M, Kenupp Bastos J, Sforcin JM. Can bee propolis help us fight against methicillin-resistant Staphylococcus aureus (MRSA)? RPS Pharm Pharmacol Reports. 2022;1:1–9.

AL-Ani I, Zimmermann S, Reichling J, Wink M. Antimicrobial activities of european propolis collected from various geographic origins alone and in combination with antibiotics. Medicines. 2018;5(1):2.

Zhang W, Margarita GE, Wu D, Yuan W, Yan S, Qi S, et al. Antibacterial activity of chinese red propolis against Staphylococcus aureus and MRSA. Molecules. 2022;27(5):1–17.

Chen YW, Ye SR, Ting C, Yu YH. Antibacterial activity of propolins from Taiwanese green propolis. J Food Drug Anal. 2018;26(2):761–8.

Bankova V, Popova M, Trusheva B. Propolis volatile compounds: Chemical diversity and biological activity: A review. Chem Cent J. 2014;8(1):1–8.

Salamanca Grosso G. Propóleos: Flora asociada. In: Origen, naturaleza, propiedades fisicoquímicas y valor terapéutico del propóleo. Ibague-Tolima: Sello Editorial Universidad del Tolima; 2017. p. 99–138.

Przybyłek I, Karpiński TM. Antibacterial properties of propolis. Molecules. 2019;24(11):1–17.

Ribeiro VP, Arruda C, Aldana-Mejia JA, Bastos JK, Tripathi SK, Khan SI, et al. Phytochemical, antiplasmodial, cytotoxic and antimicrobial evaluation of a southeast brazilian brown propolis produced by Apis mellifera bees. Chem Biodivers. 2021;18(9):1–11.

Ripari N, Flávia A, Pereira M, Júnior AF, Lúcia V, Rall M, et al. Brazilian red propolis in combination with β -lactams exerts an efficient antibacterial action over methicillin- resistant Staphylococcus aureus ( MRSA ) strains. J Appl Microbiol. 2023;134:1–12.

Veiga RS, De Mendonça S, Mendes PB, Paulino N, Mimica MJ, Lagareiro Netto AA, et al. Artepillin C and phenolic compounds responsible for antimicrobial and antioxidant activity of green propolis and Baccharis dracunculifolia DC. J Appl Microbiol. 2017;122(4):911–20.

Pamplona-Zomenhan L, Pamplona B, da Silva C, Marcucci M, Jenné L. Evaluation of the in vitro antimicrobial activity of an ethanol extract of brazilian classified propolis strains of Staphylococcus aureus. Brazilian J Microbiol. 2011;42:1259–64.

ZhangW,GomezM,YuanW,QiS,XueX,WuL. Antibacterial Activity of Chinese Red Propolis against Staphylococcus aureus and MRSA. Molecules. 2022; 27(5):1692.

Bouchelaghem S. Propolis characterization and antimicrobial activities against Staphylococcus aureus and Candida albicans: A review. Saudi Journal of Biological Sciences. 2022; 29 (4): 1936-1946.

Dezmirean D, Paşca C, Moise A, Bobi O. Plant Sources Responsible for the Chemical Composition and Main Bioactive Properties of Poplar Propolis. Plants. 2021; 10:22.

Djais A, Putri N, Rahmania Putri A, Angky Soekanto S. Description of Streptococcus mutans, Streptococcus sanguinis, and Candida albicans biofilms after exposure to propolis dentifrice by using OpenCFU method. The Saudi Dental Journal. 2019; 32:129-134.

Da Silva J, Souza M, Vidal F. Correlation analysis between phenolic levels of Brazilian propolis extracts and their antimicrobial and antioxidant activities. Food Chemistry. 2006; 99 (3):431-435.

Daikh A, Segueni N, Dogan N, Arslan S. Comparative study of antibiofilm, cytotoxic activity and chemical composition of Algerian propolis. Journal of Apicultural Research. 2020; 59:160-169.

Dantas Silva P, Machado, Gupta V. Antioxidant, antimicrobial, antiparasitic, and cytotoxic properties of various Brazilian propolis extracts. PLoS ONE. 2017:12 (3).

Nascimento Araújo C, Mayworm M, Yatsuda R. Campos Chemical composition and antimycoplasma activity of a brown propolis from southern. Brazil J Food Sci Technol. 2020; 57 (11):4228-4235.

Duarte C, Leme E, Delarmelina C, Soares A, Figueira G,.Sartoratto A. Activity of essential oils from Brazilian medicinal plants on Escherichia coli.Journal of Ethnopharmacology. 2007; 111 (2):197-201.

Bankova V. Chemical diversity of propolis and the problem of standardization. Journal of Ethnopharmacology. 2005; 100:114-117.

Béji-Srairi R, Younes I, Snoussi M, Yahyaoui K. Ethanolic extract of Tunisian propolis: chemical composition, antioxidant, antimicrobial and antiproliferative properties. Journal of Apicultural Research. 2020; 59 (5): 917-927.

Goncalves R, Cunha Pinto M. A review of the plant origins, composition and biological activity of red propolis. Natural products: Structure, bioactivity and applications. Nova Science Publishers. 2012; 1:83-96.

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Triana, L. E. ., & Lucumi, A. . (2024). Antibacterial activity of three ethanolic extracts of propolis from the municipalities of Sevilla, Cartago, and Armenia, Colombia, against MRSA (Methicillin-Resistant Staphylococcus aureus). NOVA Biomedical Sciences Journal, 22(42). https://doi.org/10.22490/24629448.8195

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Antibacterial activity of three ethanolic extracts of propolis from the municipalities of Sevilla, Cartago, and Armenia, Colombia, against MRSA (Methicillin-Resistant Staphylococcus aureus)

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