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Systematic review and bibliometric analysis of themetabolome found in human breast milk from healthy andgestational diabetes mellitus mothers
Introduction. Human breast milk is considered the gold standard of nutrition, given
that thanks to the diversity in the metabolome it manages to meet the individual needs of
each infant by providing essential metabolites that contribute to and intervene in optimal
growth and development. Few factors can modify the composition of breast milk and,
simultaneously, its benefits. However, the increase in maternal metabolic diseases such as
gestational diabetes mellitus raises the question of whether it can be one of the factors that
condition the quality and quantity of metabolites contained in breast milk. Objective. To
identify the metabolome of breast milk from healthy mothers, its influence on the growth
and development of the infant, and to recognize those that are altered because of gestatio-
nal diabetes mellitus. Methodology. A systematic review was carried out using multiple
databases. For the bibliometric analysis, we used the results of Web of Science and Scopus
and the Tree of Science and Bibliometrix software.
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