Organ transplants have been a clinical area tool for the search of the improvement of the quality in the human health and it also offers the patient a new opportunity of life. This solution has been blocked by the deficit of enough organs. To obtain them there have been big difficulties like the negative of the families, the costs, the delay in the reception of the organ, the lack of logistical infrastructure that allows to carry it in a timely fashion, the flaws in the transport of the organ risking the success of the transplant, among others. For all the above and keeping in mind the possible rejection because of the compatibility of the complex antigen to recognize among donor and receiver, the scientists have looked at organs of animals denominated xenogenics that can solve this problem and it will allow us to have an alternative for the easy obtaining of organs for people that require it. This publication tries to carry out a wide revision of the contents of the transplant with the purpose of analyzing the advantages and disadvantages of a xenogenic transplant from the molecular and immunologic point of view.
keywords:
allogeneic, histocompatibility, major histocompatibility complex (MHC), polymorphism, Tlymphocytes, xenotransplantation.
