Parámetros hematológicos de pacientes con fibrosis 2133quística de la costa caribe colombiana: análisis y asociación con aislamiento de pseudomonasaeruginosa

Zoraya Rodríguez Escobar; Luis Veloza Cabrera; Javier Baena Del Valle; Enrique Ramos; Claudio Gómez Alegría; Doris Gómez Camargo

doi:10.22490/24629448.1083

Vol. 7 No. 11 (2009)

Published 2009-06-15

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Research Article (before OJS)

Parámetros hematológicos de pacientes con fibrosis 2133quística de la costa caribe colombiana: análisis y asociación con aislamiento de pseudomonasaeruginosa

DOI: https://doi.org/10.22490/24629448.1083

Zoraya Rodríguez Escobar

Luis Veloza Cabrera

Javier Baena Del Valle

Enrique Ramos

Claudio Gómez Alegría

Doris Gómez Camargo

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Abstract
References

Hemogramme is a fundamental tool to asses cystic fibrosis (CF) patients, because multiple factors could change its parameters. The aim of this study was to analyze and describe hematologic patterns of CF patients and determinate their association with infection by Pseudomonas aeruginosa and administration of micronutrients. A conventional Hemogramme, sputum culture, medical history and physical examination were performed to 19 CF patients. 7 patients (36.8%) presented anemia, only symptomatic in one patient and mild in all cases. 4 patients (21%) received an inadequate supplementation with micronutrients. It wasn’t a significant association between anemia and micronutrients supplementation regimen with RR 0,63 CI95%(0,18 – 3,81). 4 (21%) presented leucocytosis, in 2 patients (10.5%) we found eosinophilia.

We isolated Pseudomonas aeruginosa in 8 patients (42%). Finding a significant association between anemia and infection by Pseudomonas aeruginosa with a un RR of 8,25 CI95%(1,22 – 12,06), not being significant between abnormalities in leucocytes values and Pseudomonas aeruginosa. The prevalence of anemia in our study was higher than what is reported in literature and it’s probably a ferropenic anemia, that is maybe related to infection by Pseudomonas aeruginosa, while administration of micronutrients is possibly not related with that. Lots of factors in CF patients influence levels of leucocytes without having any clinical manifestation. Chronic administration of drugs could be an important factor that could alter hematologic parameters.

keywords: anemia, cystic fibrosis, leucocytosis, micronutrients, Pseudomonas aeruginosa.

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Rodríguez Escobar, Z., Veloza Cabrera, L., Baena Del Valle, J., Ramos, E., Gómez Alegría, C., & Gómez Camargo, D. (2009). Parámetros hematológicos de pacientes con fibrosis 2133quística de la costa caribe colombiana: análisis y asociación con aislamiento de pseudomonasaeruginosa. NOVA Biomedical Sciences Journal, 7(11), 92-102. https://doi.org/10.22490/24629448.1083

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