Valor pronóstico de los marcadores bioquímicos en pacientes con COVID-19

Jennifer Carolina Gutiérrez Suárez; Carmen Cecilia Almonacid Urrego; Edith del Carmen Hernández Rojas; Hugo  Mendieta Zerón

doi:10.22490/24629448.4186

Vol. 18 Núm. 35 (2020)

Publicado 2020-09-25

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Valor pronóstico de los marcadores bioquímicos en pacientes con COVID-19

DOI: https://doi.org/10.22490/24629448.4186

Jennifer Carolina Gutiérrez Suárez

Carmen Cecilia Almonacid Urrego

Edith del Carmen Hernández Rojas

Hugo Mendieta Zerón Universidad Colegio Mayor de Cundinamarca

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El SARS-CoV-2 es un virus de la familia Coronaviridae, subfamilia coronavirus (CoV) y género β. Este se ha convertido en una amenaza inminente para toda la humanidad por ser el agente causal de la pandemia COVID-19, la cual llevó, por un lado, a la declaratoria de emergencia sanitaria a nivel mundial por parte de la Organización Mundial de la Salud (OMS) y, por otro, a instituir estrictas medidas de control para prevenir su contagio por parte de muchos gobiernos. En cuanto a la fisiopatología presentada en esta entidad, aunque las lesiones pulmonares han sido consideradas como las principales consecuencias de esta infección, a medida que avanza el conocimiento sobre el virus se han identificado también lesiones a nivel cardiaco, hepático y renal, que potencian la severidad de la infección y generan un mayor deterioro de los pacientes, su ingreso a las Unidades de Cuidados Intensivos y un mayor riesgo de mortalidad. Con base en esto, diversas investigaciones se han encaminado a determinar aquellos hallazgos clínicos y paraclínicos que puedan ser relevantes frente al pronóstico de los pacientes. Por lo anterior, la presente revisión aborda literatura disponible sobre los principales biomarcadores bioquímicos reportados por su asociación a daños cardiaco, hepático y renal, los cuales presentan mayor significancia para evaluar el curso, severidad, manejo y pronóstico de la infección, y cuya alteración conlleva finalmente a un mayor riesgo de mortalidad en pacientes hospitalizados que presentan COVID-19.

Palabras clave: diagnóstico, COVID-19, biomarcadores, rastreo, biotransformación, metabolismo

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Gutiérrez Suárez, J. C., Almonacid Urrego, C. C., Hernández Rojas , E. del C., & Mendieta Zerón, H. . (2020). Valor pronóstico de los marcadores bioquímicos en pacientes con COVID-19. Revista Nova publicación científica En Ciencias biomédicas, 18(35), 53-60. https://doi.org/10.22490/24629448.4186

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Valor pronóstico de los marcadores bioquímicos en pacientes con COVID-19

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