Estrategias diagnósticas utilizadas para detectar deficiencias de hierro subclínicas y asociadas a enfermedades crónicas

Luz Stella Coy Velandia, MSC; Martha Castillo Bohórquez, MSC; Ana Isabel Mora Bautista, MSC; Ana Lucía Oliveros R. MSC; Zulay Vélez

doi:10.22490/24629448.337

Vol. 3 Núm. 4 (2005)

Publicado 2005-12-15

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Estrategias diagnósticas utilizadas para detectar deficiencias de hierro subclínicas y asociadas a enfermedades crónicas

DOI: https://doi.org/10.22490/24629448.337

Luz Stella Coy Velandia, MSC Universidad Colegio Mayor de Cundinamarca,

Martha Castillo Bohórquez, MSC Universidad Colegio Mayor de Cundinamarca,

Ana Isabel Mora Bautista, MSC Universidad Colegio Mayor de Cundinamarca,

Ana Lucía Oliveros R. MSC Universidad Colegio Mayor de Cundinamarca,

Zulay Vélez Universidad Colegio Mayor de Cundinamarca

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La homeostasis y las variaciones fisiológicas horarias en el metabolismo del hierro se constituyen en verdaderos desafíos para los expertos, quienes intentan diseñar pruebas altamente sensibles y específicas que cuantifiquen los niveles circulantes y de depósito de este elemento, su repercusión en la eritropoyesis, cuantificación de las proteínas, transportadores y receptores involucrados en el proceso, a fin de descartar la presencia de estados carenciales. Las deficiencias de hierro pasan por tres fases; las dos primeras son las más difíciles de identificar porque son subclínicas, más aún, cuando pueden cursar simultáneamente con enfermedades crónicas inflamatorias, infecciosas y neoplásicas que de por sí son anemizantes. En este trabajo se revisarán las principales pruebas de laboratorio utilizadas para la identificación de deficiencias de hierro, sensibilidad, especificidad, ventajas y limitaciones para su uso

Palabras clave: anemia, enfermedades crónicas, deficiencia de hierro, diagnóstico, índice receptor transferrina-ferritina

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Coy Velandia, MSC, L. S., Castillo Bohórquez, MSC, M., Mora Bautista, MSC, A. I., Oliveros R. MSC, A. L., & Vélez, Z. (2005). Estrategias diagnósticas utilizadas para detectar deficiencias de hierro subclínicas y asociadas a enfermedades crónicas. Revista Nova publicación científica En Ciencias biomédicas, 3(4), 58-68. https://doi.org/10.22490/24629448.337

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