Papel de las pruebas rápidas (POCT) en el diagnóstico del SARS-COV-2, agente causal de COVID-19

Carmen Cecilia  Almonacid Urrego; María Vilma Giratá Pedraza; Irlena  Salcedo Pretelt; Isabel Cristina Almonacid Urrego

doi:10.22490/24629448.4185

Vol. 18 Núm. 35 (2020)

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2020-09-25

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Papel de las pruebas rápidas (POCT) en el diagnóstico del SARS-COV-2, agente causal de COVID-19

DOI: https://doi.org/10.22490/24629448.4185

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Carmen Cecilia Almonacid Urrego Universidad Colegio Mayor de Cundinamarca

María Vilma Giratá Pedraza

Irlena Salcedo Pretelt Colegio Mayor de Cundinamarca

Isabel Cristina Almonacid Urrego Colegio Mayor de Cundinamarca

El estándar de oro actual para la detección de SARS-CoV-2, agente causal de la pandemia de neumonía atípica (COVID-19) que apareció por primera vez en la ciudad de Wuhan (provincia de Hubei, China) en diciembre de 2019 (1), es la RT-qPCR. El protocolo estándar implica la transcripción inversa de ARN de SARS-CoV-2 en cadenas de ADN complementarias (ADNc), seguida de la amplificación de regiones específicas del ADNc. Este procedimiento demanda varias horas para ser completado y deriva en que la información final del estado de la infección pueda demorar hasta 24 horas. Ante la necesidad de disminuir el riesgo de una posible propagación viral dentro de la población originada por la rápida transmisión del SARS-CoV-2, se ha buscado prevenir el contagio, la propagación nosocomial y la transmisión comunitaria posterior, a través de la identificación rápida de casos sospechosos, y predecir las posteriores ondas infecciosas de recurrencia viral. Para esto, se vienen desarrollando métodos de laboratorio rápidos o point of care testing (POCT), que disminuyen el tiempo de diagnóstico y minimizan el riesgo de contagio por parte de los operadores.

SARS-CoV-2, coronavirus humano, Covid 19, POCT

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Almonacid Urrego, C. C. ., Giratá Pedraza, M. V., Salcedo Pretelt, I. ., & Almonacid Urrego, I. C. (2020). Papel de las pruebas rápidas (POCT) en el diagnóstico del SARS-COV-2, agente causal de COVID-19. Nova, 18(35), 43-52. https://doi.org/10.22490/24629448.4185

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