Lesión de mielomeningocele, Estudio de caso

[1] Khan YS, Lui F. (2023). Neuroanatomy of the spinal cord. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK559056/

[2] Ayyangar R, Bowman A. (2021). Myelomeningocele and other spinal dysraphisms. In: Braddom’s Physical Medicine and Rehabilitation.

Elsevier; pp. 1027-1048.e6. https://doi.org/10.1016/B978-0-323-62539- 5.00048-5

[3] Chellathurai A, Kathirvelu G, Mukkada PJ, Rajendran K, Ramani R. (2021). Spinal dysraphisms: A new anatomical-clinical-radiological classification. Indian J Radiol Imaging. 31(4):809–29. Doi:10.1055/s- 0041-1741100.

[4] Hussein NA, Ahmed KA, Osman NM, Yacoub GEE. (2022). Role of ultrasound in screening for spinal dysraphism in at-risk infants. Egypt J Radiol Nucl Med. 53(1). Doi:10.1186/s43055-022-00722-2.

[5] Ko H-Y. (2022). Neural tube defects and neurulation abnormalities. In: Management and rehabilitation of spinal cord injury. Singapore: Springer Nature Singapore; pp. 371–9. Doi:10.1007/978-981-19-0228- 4_18.

[6] Hekimoğlu G, Yücel N. (2024). HEALTH AND SCIENCE: Basic Medical Sciences -CENTRAL NERVOUS SYSTEM-. Efe Akademi Yayınları. Doi: https://doi.org/10.36283/ziun-pjmd14-1/014.

[7] Zhu T, Han J, Vasquez E. (2021). Undetected anterior sacral meningomyelocele presenting with obstructive uropathy. Urol Case Rep. 34(101434):101434. Doi:10.1016/j.eucr.2020.101434.

[8] Viskochil DH, Stevenson DA. (2020). Skeletal manifestations in NF1. In: Multidisciplinary approach to neurofibromatosis type 1. Cham: Springer International Publishing; pp. 85–99. https://dokumen.pub/multidisciplinary-approach-to-neurofibromatosis- type-1-1st-ed-9783319924496-9783319924502.html

[9] Gutiérrez-Quintana R, De Decker S. (2021). End of the brachycephalic problem: diagnostic and treatment options for spinal malformations. In practice. 43(3):124–34. Doi:10.1002/inpr.26.

[10] Agrawal A. (2022). Brain tumors. BoD – Books on demand.

[11] Tawfik NA, Ahmed AT, El-Shafei TE, et al. (2020). Diagnostic value of spinal ultrasound compared to magnetic resonance imaging for the diagnosis of spinal anomalies in pediatrics. Egypt J Radiol Nucl Med; 51:18. Doi: 10.1186/s43055-020-0131-7.

[12] Hukamdeen S, Arsalan M, Seyal S, Nasrullah Z, Ali S, Ashraf H. (2022). Diagnostic accuracy of ultrasound in detecting spina bifida and s in the first and second trimesters using postnatal magnetic resonance imaging as the gold standard. Pakistan J Med Health Sci;16(7):909–12. Doi:10.53350/pjmhs22167909.

[13] Mansoor AM, Ameer FA. (2024). Encephalocele. In: Congenital Brain Malformations. Cham: Springer Nature Switzerland; pp. 41–57.

[14] Hunsaker P, Gupta K, Otto N, Epelman MJ, Chandra T. (2023). Pediatric Spinal Developmental Anomalies: A Review of the Correlation Between Ultrasound and MRI Findings. Cureus. Doi:10.7759/cureus.44580.

[15] Kamal MA, Eltayeb M, Coulter I, Jenkins A. (2023). Surgical treatment of anterior sacral meningoceles: an illustrated case series and review of the literature. Br J Neurosurg. 1–7. Doi:10.1080/02688697.2022.2162852.

[16] Sen IM, Jangra K. (2023). Neural tube development and defects: Meningocele, encephalocele, hydrocephalus. In: Saha U, editor. Clinical Anesthesia for the Newborn and Neonate. Singapore: Springer; Doi:10.1007/978-981-19-5458-0_35.

[17] Emsen IM. (2019). Reconstructions with new and different techniques for large and extensive myelomeningocele defects. J Craniofac Surg. 30(2):584–88. Doi:10.1097/SCS.0000000000004879.

[18] Danzer E, Joyeux L, Flake AW, Deprest J. (2020). Fetal surgical intervention for myelomeningocele: lessons learned, outcomes, and future implications. Dev Med Child Neurol. 62(4):417–25. Doi:10.1111/dmcn.14429.

[19] Perin, J.; Mai, CT; De Costa, A.; Strong, K.; Diaz, T.; Blencowe, H.; Berry, RJ; Williams, JL; Liu, L. (2023). Systematic estimates of the global, regional, and national burden of under-five mortality attributable to birth defects in 2000–2019: Summary of findings from the 2020 WHO estimates. BMJ Open, 13, e067033. https://bmjopen.bmj.com/content/13/1/e067033

[20] Bai, Z.; Han, J.; An, J.; Wang, H.; Du, X.; Yang, Z.; Mo, X. (2024). Global,

regional, and national patterns of change in the burden of birth defects, 1990–2021: A 2021 global burden of disease study analysis and 2040 forecast. EClinicalMedicine, 77, 102873.

https://www.thelancet.com/journals/eclinm/article/PIIS2589- 5370(24)00452-8/fulltext

[21] Czeizel, AE; Dudas, I. (1992). Prevention of the first occurrence of neural tube defects by periconceptional vitamin supplementation. N. Engl. J.

Med. 327, 1832–1835. https://pubmed.ncbi.nlm.nih.gov/1307234/

[22] Laurence, KM; James, N.; Miller, MH; Tennant, GB; Campbell, H. (1981). Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural tube defects. Br. Med. J. (Clin. Res. Ed.), 282, 1509–1511.

https://www.bmj.com/content/282/6275/1509

[23] Kancherla, V.; Wagh, K.; Priyadarshini, P.; Pachon, H.; Oakley, GP, Jr. (2022). Global update on the status of folic acid prevention of spina bifida and anencephaly in 2020: 30th anniversary of the discovery of folic acid's potential to prevent neural tube defects. Birth Defects Res. 114, 1392–1403. https://onlinelibrary.wiley.com/doi/10.1002/bdr2.2115

[24] UNICEF: Fact sheet on under-five mortality. https://data.unicef.org/topic/child-survival/under-five-mortality/ (accessed December 8, 2025).

[25] Dabdoub CF, Dabdoub CB, Villavicencio R, Quevedo G. (2014). How I do it: myelomeningocele in Bolivia. Surg Neurol Int. Mar 10;5(Suppl 1): S39-48. Spanish. Doi:10.4103/2152-7806.128466. PMID: 24791220; PMCID: PMC3987296.

[26] Rojas, C. et al. (2025). "Clinical and sociodemographic aspects of patients with myelomeningocele in Chile." Revista Chilena de Pediatría. https://andespediatrica.cl/index.php/rchped/article/view/5327

[27] Beier, AD; Nikas, DC; Assassi, N.; Bauer, DF; Blount, JP; Durham, SR; Flannery, AM; Klimo, P.; McClung-Smith, C.; Rehring, P.; et al. (2019). Systematic review and evidence-based guideline from the Congress of Neurological Surgeons on closing myelomeningocele within 48 hours to reduce the risk of infection. Neurosurgery, 85, E412–E413. https://journals.lww.com/neurosurgery/fulltext/2019/09000/congress_of

_neurological_surgeons_systematic.20.aspx

[28] Blount, JP. George, TM. Koueik, J. Iskandar, BJ. (2019). Concepts in the neurosurgical care of patients with spinal neural tube defects: An embryologic approach. Birth Defects Res. Nov 15;111(19):1564-1576. Doi:10.1002/bdr2.1588. Epub 2019 Oct 2. PMID: 31576681.

[29] Fonseca FE, Ortega, JE. (2021). Myelomeningocele: update for clinical practice Rev. méd. Hondur. 89 (suppl, 1): 35-38. DOI: https://doi.org/10.5377/rmh.v89iSupl.1.12045

[30] Ntimbani J, Kelly A, Lekgwara P (2020). Myelomeningocele - A literature review. Interdisciplinary Neurosurgery. 19: 100-502.

https://www.sciencedirect.com/science/article/pii/S2214751919301586

[31] Tobar C, Carolina, L. (2022). Diagnosis, management, and current treatment of fetal myelomeningocele. https://www.dspace.uce.edu.ec/entities/publication/328ea96e-762d- 4a59-8cdd-a5a66617e97b

[32] Segundo, RC. García, DNB. Baena, AV. Cruz, CA. (2019). Congenital spinal malformation, myelomeningocele. Case report. Cuban Journal of Health Technology. (10)2.

https://revtecnologia.sld.cu/index.php/tec/article/view/1201

[33] Spoor, J. Gadjradj, PS. Eggink, AJ. DeKoninck, P. Lutters, B. et al. (2019) Contemporary management and outcomes of myelomeningocele: the Rotterdam experience. Neurosurgery Focus. 47(4): E3. https://pubmed.ncbi.nlm.nih.gov/31574477/

[34] Meller, C., Covini, D., Aiello, H., Izbizky, G., Portillo Medina, S., et al. (2021). Update on prenatal diagnosis and fetal surgery for myelomeningocele. Pediatrics Silver Arch. 119(3): e215-e228. https://pubmed.ncbi.nlm.nih.gov/34033426/